What is phenylpropanolamine or PPA?
Phenylpropanolamine also called PPA is an ingredient used in cold relief drugs, nasal decongestants to relieve stuffy nose or sinus congestion, appetite suppressants and dietary aids. Most of these products are sold over the counter (OTC). PPA is similar in structure to amphetamine and increases heart rate and stimulates the cardiovascular system.
How can phenylpropanolamine be unsafe when it has been sold for nearly 50 years?
A study conducted by scientists at Yale University School of Medicine for the drug companies, revealed what many had suspected. There was an increased risk of hemorrhagic stroke (bleeding of the brain) in people who took phenylpropanolamine.
Although phenylpropanolamine has been used for many years there have always been a small number of people taking the drug that have had strokes. Before the study, it was difficult to correlate the use of PPA with a stroke. The study concluded certain people who use PPA are 15 times as likely to suffer a hemorrhagic stroke as nonusers. First-time users of the ingredient are three times as likely to suffer a stroke.
Now that these numbers have been verified by scientific data the risks of using phenylpropanolamine clearly outweigh the benefits. Additionally these conclusions raise concerns over these companies continuing marketing of this product for so long without adequate testing.
Who is at the highest risk for stroke after using products that contain phenylpropanolamine?
The Yale University study showed who are the highest risk people from use of PPA products are women aged 18 to 49. Men are also at risk.
What contains phenylpropanolamine?
Phenylpropanolamine is found in many cough/cold products and OTC products for weight control. Many products now advertise that they are PPA free. Most of the PPA products have been pulled from the market. OTC products containing PPA may be identified by looking for "phenylpropanolamine" in the list of active ingredients on the label.
I have used products that contain phenylpropanolamine. Is there any danger of a stroke?
In general, the increased risk of hemorrhagic stroke occurs among women aged 18 to 49 who used weight control products. There is also a risk in using PPA products for nasal decongestion. Many of the strokes occurred within 3 days after starting to use the medication. The risk of hemorrhagic stroke is very small, but you should stop taking the drug immediately and use another product.
Can I be compensated for having a stroke or other health problems caused by PPA?
If you believe PPA (phenylpropanolamine) is related to a stroke or injury you or a loved one sustained, you may be entitled to a large compensatory award. You should protect your legal rights quickly to prevent being barred by various states' statutes of limitations.
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Overview of PPA | Health Risks and Incidence of Stroke | Full Listing of PPA Products | FDA Warning Notices
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